ABSTRACT
"AFRICAN DEVELOPMENT : The Global Fund has donated R8.8-billion to South Africa to fight HIV/Aids, tuberculosis, and malaria. The grant, which runs for three years from April 2022 until March 2025, gives a major boost to the country's efforts to eradicate these diseases. Health Minister Dr. Joe Phaahla said the government would ensure the funding was used efficiently. ""We will increase our efforts to quickly implement our programmes in HIV and TB to recover some gains which were reversed due to COVID,"" said Phaahla at the signing ceremony on Thursday"
ABSTRACT
AFRICAN DEVELOPMENT : While the rest of the world struggles to contain the spread of the Omicron variant - back home - the dreaded fourth wave came and went and South Africans could breathe a little easier. Lockdown restrictions were eased indicating a more manageable variant based on reports of less hospitalisations, and patients who experienced severe symptoms
ABSTRACT
BIRDS : The variety and widespread of coronavirus in natural reservoir animals is likely to cause epidemics via interspecific transmission, which has attracted much attention due to frequent coronavirus epidemics in recent decades. Birds are natural reservoir of various viruses, but the existence of coronaviruses in wild birds in central China has been barely studied. Some bird coronaviruses belong to the genus of Deltacoronavirus. To explore the diversity of bird deltacoronaviruses in central China, we tested faecal samples from 415 wild birds in Hunan Province, China. By RT-PCR detection, we identified eight samples positive for deltacoronaviruses which were all from common magpies, and in four of them, we successfully amplified complete deltacoronavirus genomes distinct from currently known deltacoronavirus, indicating four novel deltacoronavirus stains (HNU1-1, HNU1-2, HNU2 and HNU3). Comparative analysis on the four genomic sequences showed that these novel magpie deltacoronaviruses shared three different S genes among which the S genes of HNU1-1 and HNU1-2 showed 93.8% amino acid (aa) identity to that of thrush coronavirus HKU12, HNU2 S showed 71.9% aa identity to that of White-eye coronavirus HKU16, and HNU3 S showed 72.4% aa identity to that of sparrow coronavirus HKU17. Recombination analysis showed that frequent recombination events of the S genes occurred among these deltacoronavirus strains. Two novel putative cleavage sites separating the non-structural proteins in the HNU coronaviruses were found. Bayesian phylogeographic analysis showed that the south coast of China might be a potential origin of bird deltacoronaviruses existing in inland China. In summary, these results suggest that common magpie in China carries diverse deltacoronaviruses with novel genomic features, indicating an important source of environmental coronaviruses closed to human communities, which may provide key information for prevention and control of future coronavirus epidemics